Trametinib (GSK1120212) with Good Price CAS 871700-17-3
Product Description
Trametinib (GSK1120212) with Good Price CAS 871700-17-3
| Product name | Trametinib |
| CAS NO. | 871700-17-3 |
| Synonyms | (GSK1120212) |
| Category | Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals. |
| Purity | 99% Trametinib |
| Appearance | Trametinib powder |
| Shelf life | 2 years |
| Usage | Trametinib is an anti-cancer drug. |
| Storage | Trametinib should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
| Note | Trametinib for R&D use only. |
Function
Trametinib, also known as GSK1120212, is a n orally bioavailable inhibitor of mitogen-activated protein kinase kinase (MEK
MAPK/ERK kinase) with potential antineoplastic activity. Trametinib specifically binds to and inhibits MEK 1 and 2, resulting in
an inhibition of growth factor-mediated cell signaling and cellular proliferation in various cancers. MEK 1 and 2, dual
specificity threonine/tyrosine kinases often upregulated in various cancer cell types, play a key role in the activation of the
RAS/RAF/MEK/ERK signaling pathway that regulates cell growth.
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